Relation Results
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Summary
Name
CEP43
Full Name
Centrosomal protein 43
Synonyms
FR1OP_HUMAN | FOP
Primary ID
O95684
Links
-
-
Type
protein
Relations
2
Function
Required for anchoring microtubules to the centrosomes (PubMed:16314388, PubMed:28659385). Required for ciliation (PubMed:28625565, PubMed:28659385).
Viewer
Type:
All
Direct
Indirect
Up-regulates
Down-regulates
Binding
Transcription
Score:
0.0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
Layout:
Compact
Moderate
Relaxed
SPV
0.2
0.2
CEP43
FGFR1OP/CEP350
MAPRE1
Protein
Protein family
Complex
Chemical/Molecule
Phenotype/Stimulus
Nucleus
Membrane
Up-regulates
Down-regulates
Physical interaction
Unknown
Direct
Indirect
Binding
Search Tools
Refine search:
by mechanism
none
binding
relocalization
by effect
none
form complex
up-regulates
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
Relations
Regulator
Mechanism
target
score
ℹ
+
CEP43
form complex
binding
FGFR1OP/CEP350
0.2
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-142358
Homo sapiens
pmid
sentence
16314388
Here we show that cap350 and fop (fgfr1 oncogene partner) form a centrosomal complex required for mt anchoring.
Publications:
1
Organism:
Homo Sapiens
+
CEP43
up-regulates
relocalization
MAPRE1
0.2
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-142400
Homo sapiens
pmid
sentence
16314388
Fop also binds to eb1 and is required for localizing eb1 to the centrosome
Publications:
1
Organism:
Homo Sapiens
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