| + |
MOS | up-regulates activity
phosphorylation
|
MAP2K1 |
0.486 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-260920 |
Ser222 |
LIDSMANsFVGTRSY |
Mus musculus |
|
| pmid |
sentence |
| 7731726 |
Our data indicate that Mos activated MEK1 in vitro as well as in vivo by phosphorylating Ser 222. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
PKA | down-regulates activity
phosphorylation
|
MOS |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-260819 |
Ser73 |
LGAGGFGsVYKATYR |
Homo sapiens |
|
| pmid |
sentence |
| 8622681 |
The purified PKA catalytic subunit was able to phosphorylate recombinant p37v-mos in vitro, suggesting that the mechanism of in vivo inhibition of v-Mos kinase involves direct phosphorylation by PKA. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |