Summary

Name PENK
Full Name Proenkephalin-A [Cleaved into: Synenkephalin; Met-enkephalin
Synonyms PENK_HUMAN |
Primary ID P01210
Links - -
Type protein
Relations 1
Function Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum.

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Relations

Regulator Mechanism target score
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation PENK 0.14
Publications: 1 Organism: Homo Sapiens