4.0
Summary
| Name |  CRYAA
|
| Full Name | Alpha-crystallin A chain |
| Synonyms | Heat shock protein beta-4, HspB4 | CRYA1, HSPB4 |
| Primary ID | P02489 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Contributes to the transparency and refractive index of the lens (PubMed:18302245). In its oxidized form (absence of intramolecular disulfide bond), acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions (PubMed:22120592, PubMed:31792453). Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA (PubMed:28935373). |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
binding
