Summary

Name C1QA
Full Name Complement C1q subcomponent subunit A
Synonyms C1QA_HUMAN |
Primary ID P02745
Links - -
Type protein
Relations 2
Function C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

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Relations

Regulator Mechanism target score ℹ
+ C1QBPdown-regulates activity img/direct_inhibition.png binding C1QA 0.392
Publications: 1
+ C1QAform complex img/form-complex.png binding Complement C1q 0.628
Publications: 1 Organism: In Vitro