3.0
Summary
| Name |  APOHView Modifications |
| Full Name | Beta-2-glycoprotein 1 |
| Synonyms | APC inhibitor, Activated protein C-binding protein, Anticardiolipin cofactor, Apolipoprotein H, Apo-H, Beta-2-glycoprotein I, B2GPI, Beta(2)GPI | B2G1 |
| Primary ID | P02749 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | F10 | down-regulates activity 
cleavage
|
APOH | 0.395 |
| Publications: | 1 | Organism: | In Vitro | |
| + | PLG | down-regulates activity
cleavage
|
APOH | 0.473 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Tissue: | Blood Plasma | |||
| + | APOH | down-regulates quantity by destabilization
binding
|
cardiolipin | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |