4.0
Summary
| Name |  BZLF2
|
| Full Name | Glycoprotein 42 |
| Synonyms | gp42 | |
| Primary ID | P03205 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Pathways | EBV infection |
| Function | Plays a role in virion attachment to host B-lymphocytes, through binding to leukocyte antigen (HLA) class II and subsequently participates in fusion of the virion with host membranes. May act as a tropism switch that directs fusion with B-lymphocytes and inhibits fusion with epithelial cells. Additionally, hampers T-cell recognition via HLA class II molecules through steric hindrance of T-cell receptor-class II-peptide interaction. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | BZLF2 | form complex 
binding
|
EBV gH:gL:gp42 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Pathways: | EBV infection | |||