| + |
BZLF2 | form complex 
binding
|
EBV gH:gL:gp42 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266625 |
|
|
Homo sapiens |
B-lymphocyte |
| pmid |
sentence |
| 9151859 |
Infection of B lymphocytes by Epstein-Barr virus (EBV) requires attachment of virus via binding of viral glycoprotein gp350 to CD21 on the cell surface. Penetration of the cell membrane additionally involves a complex of three glycoproteins, gH, gL, and gp42. Glycoprotein gp42 binds to HLA-DR. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | EBV infection |
| + |
gL | form complex
binding
|
EBV gH:gL:gp42 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266627 |
|
|
Homo sapiens |
B-lymphocyte |
| pmid |
sentence |
| 9151859 |
Infection of B lymphocytes by Epstein-Barr virus (EBV) requires attachment of virus via binding of viral glycoprotein gp350 to CD21 on the cell surface. Penetration of the cell membrane additionally involves a complex of three glycoproteins, gH, gL, and gp42. Glycoprotein gp42 binds to HLA-DR. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | EBV infection |
| + |
gH | form complex
binding
|
EBV gH:gL:gp42 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266626 |
|
|
Homo sapiens |
B-lymphocyte |
| pmid |
sentence |
| 9151859 |
Infection of B lymphocytes by Epstein-Barr virus (EBV) requires attachment of virus via binding of viral glycoprotein gp350 to CD21 on the cell surface. Penetration of the cell membrane additionally involves a complex of three glycoproteins, gH, gL, and gp42. Glycoprotein gp42 binds to HLA-DR. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | EBV infection |
| + |
EBV gH:gL:gp42 | up-regulates activity 
binding
|
HLA-DRA |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266628 |
|
|
Homo sapiens |
B-lymphocyte |
| pmid |
sentence |
| 11864610 |
The EBV gp42 glycoprotein binds MHC class II molecules, playing a critical role in infection of B lymphocytes. The gp42 binds HLA-DR1 using a surface site |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | EBV infection |
| + |
EBV gH:gL:gp42 | up-regulates activity
binding
|
HLA-DRB1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266629 |
|
|
Homo sapiens |
B-lymphocyte |
| pmid |
sentence |
| 8764069 |
In EBV, the gH and gL proteins form a stable complex with a third glycoprotein, termed gp42, the product of the BZLF2 open reading frame, that appears to play a role in the infection of specific cells by EBV. The extracellular domain of BZLF2 binds specifically to a b-chain allele of the major histocompatibility complex (MHC) class II HLA-DR locus |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | EBV infection |
3.0
EBV gH:gL:gp42