Summary

Name SSB
Full Name Lupus La protein
Synonyms La autoantigen, La ribonucleoprotein, Sjoegren syndrome type B antigen, SS-B
Primary ID P05455
Links - -
Type protein
Relations 1
Function Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590). In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597).

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation SSB 0.341
Publications: 1 Organism: Homo Sapiens