Summary

Name SERPIND1
Full Name Heparin cofactor 2
Synonyms Heparin cofactor II, HC-II, Protease inhibitor leuserpin-2, HLS2, Serpin D1 | HCF2
Primary ID P05546
Links - -
Type protein
Relations 2
Function Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png cleavage SERPIND1 0.465
Publications: 1 Organism: In Vitro
+ down-regulates activity img/direct_inhibition.png cleavage SERPIND1 0.457
Publications: 1 Organism: In Vitro