Summary

Name KRT18
Full Name Keratin, type I cytoskeletal 18
Synonyms Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18 | CYK18
Primary ID P05783
Links - -
Type protein
Relations 6
Function Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

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▶Modifications Tables

Relations


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Regulator Mechanism target score ℹ
+ CDK1up-regulates img/direct-activation.png phosphorylation KRT18 0.331
Publications: 1 Organism: Homo Sapiens
+ PRKCE