3.0
Summary
| Name |  KRT18View Modifications |
| Full Name | Keratin, type I cytoskeletal 18 |
| Synonyms | Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18 | CYK18 |
| Primary ID | P05783 |
| Links |  -  -  |
| Type | protein |
| Relations | 6 |
| Function | Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CDK1 | up-regulates 
phosphorylation
|
KRT18 | 0.344 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CAMK1 |
phosphorylation
|
KRT18 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PRKCE |
phosphorylation
|
KRT18 | 0.334 |
| Publications: | 1 | Organism: | In Vitro | |
| + | PRKCA |
phosphorylation
|
KRT18 | 0.311 |
| Publications: | 1 | Organism: | In Vitro | |
| + | RPS6KA3 |
phosphorylation
|
KRT18 | 0.304 |
| Publications: | 1 | Organism: | In Vitro | |
| + | CAMK2A |
phosphorylation
|
KRT18 | 0.289 |
| Publications: | 1 | |||