| + |
APRT | down-regulates quantity 
chemical modification
|
adenine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280464 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15196008 |
In mammals, adenine phosphoribosyltransferase (APRT, EC 2.4.2.7) is present in all tissues and provides the only known mechanism for the metabolic salvage of adenine resulting from the polyamine biosynthesis pathway or from dietary sources. Phosphoribosyltransferases (PRTases) catalyze the displacement of a PRPP α-1‘-pyrophosphate through a nitrogen-containing nucleophile. The reaction products are a β-1-substituted ribose 5‘-phosphate and a free pyrophosphate (PP) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
APRT | down-regulates quantity
chemical modification
|
5-phospho-α-D-ribose 1-diphosphate |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280465 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15196008 |
In mammals, adenine phosphoribosyltransferase (APRT, EC 2.4.2.7) is present in all tissues and provides the only known mechanism for the metabolic salvage of adenine resulting from the polyamine biosynthesis pathway or from dietary sources. Phosphoribosyltransferases (PRTases) catalyze the displacement of a PRPP α-1‘-pyrophosphate through a nitrogen-containing nucleophile. The reaction products are a β-1-substituted ribose 5‘-phosphate and a free pyrophosphate (PP) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
APRT | up-regulates quantity 
chemical modification
|
AMP |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280466 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15196008 |
In mammals, adenine phosphoribosyltransferase (APRT, EC 2.4.2.7) is present in all tissues and provides the only known mechanism for the metabolic salvage of adenine resulting from the polyamine biosynthesis pathway or from dietary sources. Phosphoribosyltransferases (PRTases) catalyze the displacement of a PRPP α-1‘-pyrophosphate through a nitrogen-containing nucleophile. The reaction products are a β-1-substituted ribose 5‘-phosphate and a free pyrophosphate (PP) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
APRT | up-regulates quantity
chemical modification
|
diphosphate(3-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280467 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15196008 |
In mammals, adenine phosphoribosyltransferase (APRT, EC 2.4.2.7) is present in all tissues and provides the only known mechanism for the metabolic salvage of adenine resulting from the polyamine biosynthesis pathway or from dietary sources. Phosphoribosyltransferases (PRTases) catalyze the displacement of a PRPP α-1‘-pyrophosphate through a nitrogen-containing nucleophile. The reaction products are a β-1-substituted ribose 5‘-phosphate and a free pyrophosphate (PP) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
APRT
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