Summary

Name TPM2
Full Name Tropomyosin beta chain
Synonyms Beta-tropomyosin, Tropomyosin-2 | TMSB
Primary ID P07951
Links - -
Type protein
Relations 1
Function Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization.

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation TPM2 0.34
Publications: 1 Organism: In Vitro