| + |
EP300 | up-regulates quantity by expression 
transcriptional regulation
|
KRT16 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253904 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 12954631 |
these results suggest that Sp1 and AP1 sites in the essential promoter region are critical for EGF response, and Sp1 showed a functional cooperation with c-Jun and coactivators p300/CBP in driving the transcriptional regulation of EGF-induced keratin 16 gene expression. The coactivators p300/CBP could collaborate with Sp1 and c-Jun in the activation of keratin 16 promoter. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SP1 | up-regulates quantity by expression
transcriptional regulation
|
KRT16 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253903 |
|
|
Homo sapiens |
HaCaT Cell |
| pmid |
sentence |
| 12954631 |
these results suggest that Sp1 and AP1 sites in the essential promoter region are critical for EGF response, and Sp1 showed a functional cooperation with c-Jun and coactivators p300/CBP in driving the transcriptional regulation of EGF-induced keratin 16 gene expression. The coactivators p300/CBP could collaborate with Sp1 and c-Jun in the activation of keratin 16 promoter. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
JUN | up-regulates quantity by expression
transcriptional regulation
|
KRT16 |
0.271 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253905 |
|
|
Homo sapiens |
HaCaT Cell |
| pmid |
sentence |
| 12954631 |
these results suggest that Sp1 and AP1 sites in the essential promoter region are critical for EGF response, and Sp1 showed a functional cooperation with c-Jun and coactivators p300/CBP in driving the transcriptional regulation of EGF-induced keratin 16 gene expression. The coactivators p300/CBP could collaborate with Sp1 and c-Jun in the activation of keratin 16 promoter. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NFE2L2 | up-regulates quantity by expression
transcriptional regulation
|
KRT16 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254645 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 18629308 |
When overexpressed in HaCaT cells, NRF2 was also directly involved in not only the up-regulation of the detoxification gene thioredoxin but also K16 gene expression. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
KRT16
- 
- 