| + |
CSNK2A1 | down-regulates activity 
phosphorylation
|
MYB |
0.332 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-250918 |
Ser11 |
RPRHSIYsSDEDDED |
in vitro |
|
| pmid |
sentence |
| 7735324 |
For c-Myb mutational analysis of the CKII phosphorylation sites showed altered steady state DNA binding. Replacing Ser-11/12 by alanine residues resulted in increased DNA binding compared to wt c-Myb or Myb Asp-11/12 as demonstrated by up to 10-fold differences in the dissociation constants. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-250919 |
Ser12 |
PRHSIYSsDEDDEDF |
in vitro |
|
| pmid |
sentence |
| 7735324 |
For c-Myb mutational analysis of the CKII phosphorylation sites showed altered steady state DNA binding. Replacing Ser-11/12 by alanine residues resulted in increased DNA binding compared to wt c-Myb or Myb Asp-11/12 as demonstrated by up to 10-fold differences in the dissociation constants. |
|
| Publications: |
2 |
Organism: |
In Vitro |
| + |
ERK1/2 | down-regulates
phosphorylation
|
MYB |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-244569 |
Ser532 |
KIKQEVEsPTDKSGN |
Homo sapiens |
JURKAT Cell |
| pmid |
sentence |
| 8960373 |
Functional analysis of phosphorylation at serine 532 of human c-myb by map kinase. expression of a polypeptide containing the c-myb c-terminal domain stimulated c-myb activity. This effect is reduced upon mapk-dependent phosphorylation of serine 532. Our data suggest that the mapk-dependent state of phosphorylation modifies the cellular function of c-myb by modulating its interaction with a putative inhibitory factor |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MAPK1 |
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Stack trace:
#0 /home/prisca/signor/relation_result.php(2084): implode()
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thrown in /home/prisca/signor/relation_result.php on line 2084
4.0
MYB
- 
- 