4.0
Summary
| Name |  IAPPView Modifications |
| Full Name | Islet amyloid polypeptide |
| Synonyms | Amylin, Diabetes-associated peptide, DAP, Insulinoma amyloid peptide | |
| Primary ID | P10997 |
| Links |  -  -  |
| Type | protein |
| Relations | 5 |
| Function | Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PCSK2 | up-regulates activity 
cleavage
|
IAPP | 0.467 |
| Publications: | 1 | Organism: | In Vitro | |
| + | PCSK1 | up-regulates activity
cleavage
|
IAPP | 0.447 |
| Publications: | 1 | Organism: | In Vitro | |
| + | IAPP | up-regulates activity
binding
|
Amylin receptor 1 complex | 0.679 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | IAPP | up-regulates activity
binding
|
Amylin receptor 3 complex | 0.637 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | IAPP | up-regulates activity
binding
|
Amylin receptor 2 complex | 0.679 |
| Publications: | 1 | Organism: | Homo Sapiens | |