Summary

Name RALB
Full Name Ras-related protein Ral-B
Synonyms RALB_HUMAN
Primary ID P11234
Links - -
Type protein
Relations 1
Function Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles (By similarity). Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells (By similarity). Required for suppression of apoptosis (PubMed:17875936). In late stages of cytokinesis, upon completion of the bridge formation between dividing cells, mediates exocyst recruitment to the midbody to drive abscission (PubMed:18756269).

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ img/unknown.png phosphorylation RALB 0.18
Publications: 1 Organism: Homo Sapiens
Tissue: Lung