| + |
NPPA | up-regulates 
binding
|
NPR1 |
0.887 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-137600 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15911069 |
Natriuretic peptide receptor-a (npra) is the biological receptor of the peptide hormones atrial natriuretic peptide (anp) and brain natriuretic peptide (bnp) |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NPR1 | up-regulates activity
phosphorylation
|
ORM1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-278966 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23363605 |
On TORC1 inhibition by rapamycin treatment or nutrient limitation, Npr1 phosphorylates and activates Orm1 and Orm2, which in turn promotes synthesis of complex sphingolipids downstream of SPT.|Thus Npr1 directly phosphorylates Orm1 and Orm2 downstream of TORC1. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NPR1 | down-regulates activity 
phosphorylation
|
ART1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-279239 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 33024932 |
Art1 is a substrate for the kinase Npr1, which phosphorylates Art1 and, thereby, causes its inactivation by limiting its plasma membrane association. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NPR1 | up-regulates activity
phosphorylation
|
ORM2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-279747 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 23363605 |
On TORC1 inhibition by rapamycin treatment or nutrient limitation, Npr1 phosphorylates and activates Orm1 and Orm2, which in turn promotes synthesis of complex sphingolipids downstream of SPT.|Thus Npr1 directly phosphorylates Orm1 and Orm2 downstream of TORC1. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
NPR1
- 
- 