Summary

Name ITGA2
Full Name Integrin alpha-2
Synonyms CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha | CD49B
Primary ID P17301
Links - -
Type protein
Relations 3
Function Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.; FUNCTION

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation ITGA2 0.14
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding A2/b1 integrin 0.14
Publications: 1
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation ITGA2 0.14
Publications: 1 Organism: Homo Sapiens