+ |
ZNF76 | up-regulates quantity by expression
transcriptional regulation
|
TCP1 |
0.355 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266221 |
|
|
Homo sapiens |
|
pmid |
sentence |
10893243 |
The transcription from the minimalCcta promoter was up-regulated 3-fold by ZNF143 and 6-fold by ZNF76 when full-length proteins were co-expressed, indicating that both ZNF143 and ZNF76 can enhance Ccta transcription. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
TCP1 | form complex
binding
|
TRiC |
0.741 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-272863 |
|
|
Homo sapiens |
|
pmid |
sentence |
36185250 |
Mammalian cells contain an evolutionarily conserved type II chaperonin called chaperonin containing tailless complex polypeptide 1 (CCT) or tailless complex polypeptide 1 ring complex (TRiC). The CCT complex is composed of eight subunits [CCT1-8 (yeast) or CCTα-θ (mammals)] and folds substrates needed for cell invasion and proliferation, such as actin, tubulin, and cell division cycle protein 20 homolog (cdc20), as well as oncoproteins like signal transducer and activator of transcription 3 (STAT3), Kirsten rat sarcoma viral oncogene homolog (KRAS), and Myelocytomatosis (MYC). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
ZNF143 | up-regulates quantity by expression
transcriptional regulation
|
TCP1 |
0.283 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266220 |
|
|
Homo sapiens |
|
pmid |
sentence |
10893243 |
The transcription from the minimalCcta promoter was up-regulated 3-fold by ZNF143 and 6-fold by ZNF76 when full-length proteins were co-expressed, indicating that both ZNF143 and ZNF76 can enhance Ccta transcription. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |