Summary

Name TCP1
Full Name T-complex protein 1 subunit alpha
Synonyms TCP-1-alpha, CCT-alpha | CCT1, CCTA
Primary ID P17987
Links - -
Type protein
Relations 3
Function Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444). As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable).

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation TCP1 0.283
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation TCP1 0.355
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding TRiC 0.741
Publications: 1 Organism: Homo Sapiens