Summary

Name GABRB1
Full Name Gamma-aminobutyric acid receptor subunit beta-1
Synonyms GABA(A) receptor subunit beta-1 |
Primary ID P18505
Links - -
Type protein
Relations 6
Function Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding GABA-A (a3-b1-g2) receptor 0.597
Publications: 1 Organism: Homo Sapiens
Tissue: Central Nervous System
+ form complex img/form-complex.png binding GABA-A (a2-b1-g2) receptor 0.603
Publications: 1 Organism: Homo Sapiens
Tissue: Central Nervous System
+ form complex img/form-complex.png binding GABA-A (a5-b1-g2) receptor 0.627
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding GABA-A (a6-b1-g2) receptor 0.599
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding GABA-A (a4-b1-g2) receptor 0.604
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding GABA-A (a1-b1-g2) receptor 0.629
Publications: 1 Organism: Homo Sapiens
Tissue: Central Nervous System