Summary

Name SON
Full Name Protein SON
Synonyms Bax antagonist selected in saccharomyces 1, BASS1, Negative regulatory element-binding protein, NRE-binding protein, Protein DBP-5, SON3 | C21orf50, DBP5, KIAA1019, NREBP
Primary ID P18583
Links - -
Type protein
Relations 1
Function RNA-binding protein that acts as a mRNA splicing cofactor by promoting efficient splicing of transcripts that possess weak splice sites. Specifically promotes splicing of many cell-cycle and DNA-repair transcripts that possess weak splice sites, such as TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A, and FANCG. Probably acts by facilitating the interaction between Serine/arginine-rich proteins such as SRSF2 and the RNA polymerase II. Also binds to DNA; binds to the consensus DNA sequence

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding SON 0.241
Publications: 1 Organism: Homo Sapiens