Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-248912 |
Ser405 |
VTVSRASsSRSVRTT |
Homo sapiens |
Leukemia Cell |
pmid |
sentence |
8034666 |
Beta II PKC-mediated phosphorylation of lamin B is confined to two sites, Ser395 and Ser405 | Comparative tryptic phosphopeptide mapping demonstrates that the beta II PKC site, Ser405, is a prominent target of mitotic lamin B phosphorylation in vivo. beta II PKC translocates to the nucleus during the G2/M phase of cell cycle concomitant with phosphorylation of Ser405, indicating a physiologic role for nuclear beta II PKC activation in mitotic lamin B phosphorylation in vivo. |
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