| + |
GSK3B | down-regulates 
phosphorylation
|
NEB |
0.315 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-175659 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21798082 |
Gsk3b is able to phosphorylate nebulin at two ser sites in the c-terminal region of nebulin localized to the z-disk, thus preventing the interaction of nebulin with neuronal wiscott-aldrich syndrome protein (nwasp), a ubiquitously expressed member of the wasp family, which is involved in actin assembly. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
NEB | up-regulates 
binding
|
WASL |
0.364 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-175671 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 21798082 |
Igf1-akt signaling, by inhibiting gsk3b, allows the interaction of n-wasp with the unphosphorylated nebulin;the consequent recruitment of n-wasp to the z-disk promotes actin nucleation and elongation of actin filaments. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
NEB
- 
- 