Relation Results

Summary

Name UGT1A4
Full Name UDP-glucuronosyltransferase 1A4
Synonyms UDPGT 1-4, UGT1*4, UGT1-04, UGT1.4, Bilirubin-specific UDPGT isozyme 2, hUG-BR2, UDP-glucuronosyltransferase 1-D, UGT-1D, UGT1D, UDP-glucuronosyltransferase 1A4 | GNT1, UGT1
Primary ID P22310
Links - -
Type protein
Relations 2
Function [Isoform 1]

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Type: Score: Layout: SPV 
0.3040.2ESR1UGT1A4SP1

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Relations
Regulator
Mechanism
target
score ℹ
+ ESR1up-regulates quantity by expression img/indirect-activation.png transcriptional regulation UGT1A4 0.304
Identifier Residue Sequence Organism Cell Line
SIGNOR-254075 Homo sapiens Hep-G2 Cell
pmid sentence
our data indicate that up-regulation of UGT1A4 expression by E(2) is mediated by both ER alpha and Sp1 and is a potential mechanism contributing to the enhanced elimination of lamotrigine in pregnancy.
Publications: 1 Organism: Homo Sapiens
+ SP1up-regulates quantity by expression img/indirect-activation.png transcriptional regulation UGT1A4 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-254076 Homo sapiens Hep-G2 Cell
pmid sentence
our data indicate that up-regulation of UGT1A4 expression by E(2) is mediated by both ER alpha and Sp1 and is a potential mechanism contributing to the enhanced elimination of lamotrigine in pregnancy.
Publications: 1 Organism: Homo Sapiens
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