Summary

Name TCEA1
Full Name Transcription elongation factor A protein 1
Synonyms Transcription elongation factor S-II protein 1, Transcription elongation factor TFIIS.o | GTF2S, TFIIS
Primary ID P23193
Links - -
Type protein
Relations 1
Function Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.

Viewer

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding UBR5 0.32
Publications: 1 Organism: Homo Sapiens