3.0
Summary
| Name |  TUBG1View Modifications |
| Full Name | Tubulin gamma-1 chain |
| Synonyms | Gamma-1-tubulin, Gamma-tubulin complex component 1, GCP-1 | TUBG |
| Primary ID | P23258 |
| Links |  -  -  |
| Type | protein |
| Relations | 7 |
| Inhibitors | vincaleukoblastine sulfate |
| Function | Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | BRSK1 | up-regulates 
phosphorylation
|
TUBG1 | 0.251 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | g-TuRC complex | up-regulates activity
binding
|
TUBG1 | 0.864 |
| Publications: | 1 | Organism: | In Vitro | |
| + | vincaleukoblastine sulfate | down-regulates activity 
chemical inhibition
|
TUBG1 | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | NUP62 | up-regulates activity
binding
|
TUBG1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | TUBG1 | up-regulates 
|
Microtubule_polimerization | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | NUMA1 | up-regulates
binding
|
TUBG1 | 0.604 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CDK5RAP2 | up-regulates activity
binding
|
TUBG1 | 0.637 |
| Publications: | 1 | Organism: | Homo Sapiens | |