3.0
Summary
| Name |  CXCR1
|
| Full Name | C-X-C chemokine receptor type 1 |
| Synonyms | CXC-R1, CXCR-1, CDw128a, High affinity interleukin-8 receptor A, IL-8R A, IL-8 receptor type 1 | CMKAR1, IL8RA |
| Primary ID | P25024 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Pathways | Chemokines PDAC |
| Function | Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. |
binding