3.0
Summary
| Name |  CTNNA2
|
| Full Name | Catenin alpha-2 |
| Synonyms | Alpha N-catenin, Alpha-catenin-related protein | CAPR |
| Primary ID | P26232 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system (By similarity). Required for proper regulation of cortical neuronal migration and neurite growth (PubMed:30013181). It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization (PubMed:30013181). It thereby suppresses excessive actin branching which would impair neurite growth and stability (PubMed:30013181). Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation (By similarity). |
binding