Relation Results

Summary

Name PSMA5
Full Name Proteasome subunit alpha type-5
Synonyms Macropain zeta chain, Multicatalytic endopeptidase complex zeta chain, Proteasome zeta chain
Primary ID P28066
Links - -
Type protein
Relations 2
Function Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essen ...
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Type: Score: Layout: SPV 
0.3050.87PSMA5XBP126S Proteasome

Relations

Regulator
Mechanism
target
score
+ down-regulates quantity by destabilization img/direct_inhibition.png binding XBP1 0.305
Identifier Residue Sequence Organism Cell Line
SIGNOR-239213 in vitro
pmid sentence
We saw preferential binding of XBP-1u to subunits _5, _6 and _7.2. We demonstrate that XBP-1u undergoes efficient degradation in vitro by 20S proteasomes in the absence of ubiquitination.
Publications: 1 Organism: In Vitro
+ form complex img/form-complex.png binding 26S Proteasome 0.87
Identifier Residue Sequence Organism Cell Line
SIGNOR-263364 Homo sapiens HEK-293 Cell
pmid sentence
Here, we report near-atomic resolution cryo-EM structures of the activated human proteasome|The proteasome is composed of a 28-subunit barrel-shaped core particle (CP) and two 19- subunit regulatory particles (RP)5–8 capped at both sides of the CP|Human proteasomes were purified through affinity chromatography on a large scale from a stable HEK293 cell line
Publications: 1 Organism: Homo Sapiens
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