| + |
HOXD3 | up-regulates quantity by expression 
transcriptional regulation
|
A5/b1 integrin |
0.253 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261650 |
|
|
Homo sapiens |
HMEC-1 Cell |
| pmid |
sentence |
| 14610084 |
The homeobox transcription factor Hox D3 promotes integrin alpha5beta1 expression and function during angiogenesis. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
HOXD3 | up-regulates quantity by expression
transcriptional regulation
|
ITGA5 |
0.253 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261649 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 14610084 |
The homeobox transcription factor Hox D3 promotes integrin alpha5beta1 expression and function during angiogenesis. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
HMGB1 | up-regulates activity
binding
|
HOXD3 |
0.301 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-219980 |
|
|
in vitro |
|
| pmid |
sentence |
| 8890171 |
We show that HMG1 interacts with proteins encoded by the HOX gene family by establishing protein-protein contacts between the HMG box domains and the HOX homeodomain. The functional role of these interactions was studied using the transcriptional activity of the human HOXD9 protein as a model. HMG1 enhances, in a dose-dependent fashion, the sequence-specific DNA binding activity in vitro, and the transcriptional activation in a co-transfection assay in vivo, of the HOXD9 protein. |
|
| Publications: |
1 |
Organism: |
In Vitro |
3.0
HOXD3
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