4.0
Summary
| Name |  PRKAR2BView Modifications |
| Full Name | cAMP-dependent protein kinase type II-beta regulatory subunit |
| Synonyms | KAP3_HUMAN |
| Primary ID | P31323 |
| Links |  -  -  |
| Type | protein |
| Relations | 6 |
| Inhibitors | 3',5'-cyclic AMP |
| Function | Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PRKACA | up-regulates activity 
phosphorylation
|
PRKAR2B | 0.885 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PRKAR2B | up-regulates activity
phosphorylation
|
PRKAR2B | 0.2 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | PRKAR2B | down-regulates activity 
binding
|
PRKACA | 0.885 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PRKAR2B | down-regulates activity
binding
|
PRKACB | 0.897 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PJA2 | down-regulates quantity by destabilization
polyubiquitination
|
PRKAR2B | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | 3',5'-cyclic AMP | down-regulates activity
chemical inhibition
|
PRKAR2B | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |