+ |
alemtuzumab | down-regulates activity
binding
|
CD52 |
0.4 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-259883 |
|
|
Homo sapiens |
T-lymphocyte, B-lymphocyte |
pmid |
sentence |
15757437 |
Alemtuzumab is a humanized monoclonal antibody against CD52, a small glycosylphosphatidylinositol-anchored glycoprotein that is highly expressed on normal T- and B-lymphocytes, and on a large proportion of malignant lymphoid cells, but not on hematopoietic progenitor cells. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
SATB1 | up-regulates quantity by expression
transcriptional regulation
|
CD52 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-255131 |
|
|
Homo sapiens |
K-562 Cell |
pmid |
sentence |
17343824 |
We found 59 up-regulated and 75 down-regulated genes in the K562-SATB1 cells that were not observed in the K562 cells. Partial genes that have special biological functions are listed in Table 1. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |