3.0
Summary
| Name |  APOBEC3A
|
| Full Name | DNA dC->dU-editing enzyme APOBEC-3A |
| Synonyms | A3A, Phorbolin-1 | |
| Primary ID | P31941 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. |
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ubiquitination
