| Name
|
 SOAT1
|
| Full Name |
Sterol O-acyltransferase 1 |
| Synonyms |
Acyl-coenzyme A:cholesterol acyltransferase 1, ACAT-1, Cholesterol acyltransferase 1 | ACACT, ACACT1, ACAT, ACAT1, SOAT, STAT |
| Primary ID |
P35610 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
3 |
| Inhibitors |
Avasimibe
|
| Function |
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol (PubMed:16154994, PubMed:16647063, PubMed:9020103, PubMed:32433614, PubMed:32433613). Plays a role in lipoprotein assembly and dietary cholesterol absorption (PubMed:16154994, PubMed:9020103). Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) preferentially as susbstrate |
4.0
chemical activation
chemical modification