3.0
Summary
| Name |  NUP62View Modifications |
| Full Name | Nuclear pore glycoprotein p62 |
| Synonyms | 62 kDa nucleoporin, Nucleoporin Nup62 | |
| Primary ID | P37198 |
| Links |  -  -  |
| Type | protein |
| Relations | 7 |
| Function | Essential component of the nuclear pore complex (PubMed:1915414). The N-terminal is probably involved in nucleocytoplasmic transport (PubMed:1915414). The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex (PubMed:1915414, PubMed:24107630). Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation (PubMed:24107630). It might be involved in protein recruitment to the centrosome after nuclear breakdown (PubMed:24107630). |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | MAPK12 | down-regulates quantity by destabilization 
phosphorylation
|
NUP62 | 0.2 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | NUTF2 | up-regulates activity 
binding
|
NUP62 | 0.84 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | NUP62 | form complex 
binding
|
NPC | 0.697 |
| Publications: | 1 | |||
| + | NUP62 | up-regulates activity
binding
|
SASS6 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | NUP62 | form complex
binding
|
p62_complex | 0.938 |
| Publications: | 1 | Organism: | Rattus Norvegicus | |
| + | NUP62 | up-regulates activity
binding
|
TUBG1 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |