Summary

Name IL15
Full Name Interleukin-15
Synonyms IL-15
Primary ID P40933
Links - -
Type protein
Relations 2
Pathways FAP: IL15
Function Cytokine that stimulates the proliferation of T-lymphocytes (PubMed:8178155). Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (PubMed:8178155). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation (PubMed:15123770).

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding IL15RA 0.861
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle, Skeletal Muscle
+ up-regulates img/direct-activation.png binding IL2RG 0.846
Publications: 1 Organism: Homo Sapiens