3.0
Summary
| Name |  PMEL
|
| Full Name | Melanocyte protein PMEL |
| Synonyms | ME20-M, ME20M, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, P1, P100, Premelanosome protein, Silver locus protein homolog | D12S53E, PMEL17, SILV |
| Primary ID | P40967 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity. |
transcriptional regulation