Summary

Name NSF
Full Name Vesicle-fusing ATPase
Synonyms N-ethylmaleimide-sensitive fusion protein, NEM-sensitive fusion protein, Vesicular-fusion protein NSF
Primary ID P46459
Links - -
Type protein
Relations 2
Function Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity).

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png dephosphorylation NSF 0.423
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding SNAP25 0.753
Publications: 1 Organism: Homo Sapiens