Summary

Name MAP1B
Full Name Microtubule-associated protein 1B
Synonyms MAP-1B
Primary ID P46821
Links - -
Type protein
Relations 1
Function Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding MAP1B 0.34
Publications: 1 Organism: Homo Sapiens