Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-266848 |
|
|
Mus musculus |
Cerebellar Purkinje Cell |
pmid |
sentence |
19381306 |
RORα regulates the expression of several genes in Purkinje cells. RORα becomes highly expressed in postmitotic Purkinje cells. It regulates their maturation, particularly dendritic differentiation. Dendritogenesis and the expression of several genes, including Shh, Itpr1, Pcp4, Calb1, Pcp2, and Slc1a6, normally expressed in mature Purkinje cells, are inhibited in RORα-deficient mice. |
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