Relation Results

Summary

Name KCNC1
Full Name Potassium voltage-gated channel subfamily C member 1
Synonyms NGK2, Voltage-gated potassium channel subunit Kv3.1, Voltage-gated potassium channel subunit Kv4 |
Primary ID P48547
Links - -
Type protein
Relations 1
Function Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response t ...
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Type: Score: Layout: SPV 
0.8KCNC1potassium(1+)

Relations

Regulator
Mechanism
target
score
+ down-regulates quantity img/direct_inhibition.png relocalization potassium(1+) 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-265586 Homo sapiens
pmid sentence
Kv3 currents are activated specifically during action potential repolarization. Analysis of the Kv3 subfamily of K+ channel subunits has lead to the discovery of a new class of neuronal voltage-gated K+ channels characterized by positively shifted voltage dependencies and very fast deactivation rates. These properties are adaptations that allow these channels to produce currents that can specifically enable fast repolarization of action potentials without compromising spike initiation or height
Publications: 1 Organism: Homo Sapiens
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