Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration.
This interaction may facilitate cell activation and migration through the blood-brain barrier. In addition, cd97-cd55 interactions in the parenchyma of the brain may contribute to the inflammation.
This approach led us to the discovery that CD97, a pro-metastatic adhesion G-protein coupled receptor (GPCR), is a direct target of miR-126.| These results confirm the binding site for miR-126 in the 3’-UTR OF CD97