+ |
PKNOX1 | up-regulates activity
binding
|
HOXA1 |
0.57 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-220242 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
9582372 |
Our results are consistent with a primary interaction of the YPWM motif of HOXA1 with the homeodomain of PBX. HOX proteins are dependent upon cofactors of the PBX family for specificity of DNA binding. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
KDM6A | up-regulates quantity by expression
transcriptional regulation
|
HOXA1 |
0.376 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-260019 |
|
|
Homo sapiens |
|
pmid |
sentence |
24561908 |
Evidence for direct involvement of UTX in regulation of HOX gene activity was demonstrated through UTX knockdown experiments in HEK293T cells in which loss of UTX induced transcriptional repression of HOXA and HOXC clusters. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |