Summary

Name HOXA1
Full Name Homeobox protein Hox-A1
Synonyms Homeobox protein Hox-1F | HOX1F
Primary ID P49639
Links - -
Type protein
Relations 2
Function Sequence-specific transcription factor (By similarity). Regulates multiple developmental processes including brainstem, inner and outer ear, abducens nerve and cardiovascular development and morphogenesis as well as cognition and behavior (PubMed:16155570). Also part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. Seems to act in the maintenance and/or generation of hindbrain segments (By similarity). Activates transcription in the presence of PBX1A and PKNOX1 (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding HOXA1 0.57
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation HOXA1 0.376
Publications: 1 Organism: Homo Sapiens