+ |
RNF144A | down-regulates quantity by destabilization
polyubiquitination
|
PRKDC |
0.548 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-272213 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
24979766 |
We show that RNF144A induces ubiquitination of DNA-PKcs in vitro and in vivo and promotes its degradation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
Ub:E2 | up-regulates activity
ubiquitination
|
RNF144A |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-271154 |
|
|
Homo sapiens |
|
pmid |
sentence |
34199813 |
The ubiquitination process is mediated sequentially by three classes of enzymes consisting of a Ub-activating enzyme E1, a Ub-conjugating enzyme E2, and a Ub ligase E3. Ub is first activated by E1 in an adenosine 5′-triphosphate (ATP)-dependent manner t |
|
Publications: |
1 |
Organism: |
Homo Sapiens |