Relation Results

Summary

Name RAB5C
Full Name Ras-related protein Rab-5C
Synonyms L1880, RAB5L | RABL
Primary ID P51148
Links - -
Type protein
Relations 2
Function Protein transport. Probably involved in vesicular traffic (By similarity).

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Type: Score: Layout: SPV 
0.20.829LYSTRAB5CEEA1

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Relations
Regulator
Mechanism
target
score ℹ
+ LYSTdown-regulates activity img/direct_inhibition.png binding RAB5C 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-266003 Drosophila melanogaster
pmid sentence
Mauve interacts with Rab5, Msps, and gamma-tubulin|Mauve/LYST opposes Rab5, which promotes vesicle fusion affecting PCM recruitment
Publications: 1 Organism: Drosophila Melanogaster
+ RAB5Cup-regulates activity img/direct-activation.png binding EEA1 0.829
Identifier Residue Sequence Organism Cell Line
SIGNOR-261266 in vitro
pmid sentence
The Rab5 effector early endosome antigen 1 (EEA1) is a parallel coiled coil homodimer with an N-terminal C(2)H(2) Zn(2+) finger and a C-terminal FYVE domain. Rab5 binds to independent sites at the N and C terminus of EEA1.|The results demonstrate that the C(2)H(2) Zn(2+) finger is both essential and sufficient for the N-terminal interaction with Rab5.
Publications: 1 Organism: In Vitro
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