| Name
|
 CCR4
|
| Full Name |
C-C chemokine receptor type 4 |
| Synonyms |
C-C CKR-4, CC-CKR-4, CCR-4, CCR4, K5-5 | CMKBR4 |
| Primary ID |
P51679 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
1 |
| Function |
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. |
3.0
binding