| + |
CAMK2A | up-regulates activity 
phosphorylation
|
CLCN3 |
0.348 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-275863 |
Ser109 |
ERHRRINsKKKESAW |
|
|
| pmid |
sentence |
| 14754994 |
Identification of an N-terminal amino acid of the CLC-3 chloride channel critical in phosphorylation-dependent activation of a CaMKII-activated chloride current|The N-terminus of CLC-3, which contains a CaMKII consensus sequence, was phosphorylated by CaMKII in vitro, and mutation of the serine at position 109 (S109A) abolished the CaMKII-dependent Cl(-) conductance, indicating that this residue is important in the gating of CLC-3 at the plasma membrane. |
|
| Publications: |
1 |
| + |
CLCN3 | down-regulates quantity 
relocalization
|
chloride |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265422 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 29845874 |
ClC-3 is a strongly outwardly rectifying, electrogenic 2Cl/H exchanger with biophysical properties that closely resemble those of its close homologues ClC-4 and ClC-5 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
CLCN3
- 
- 